Chapman 2021 – Orthodontic trials: Are we measuring the right things? Aliki Tsichlaki
Join me for Aliki’s prize winning lecture looking at orthodontic outcomes in research.
Lecture based on the paper by Aliki:
Development of core outcome set for use in routine orthodontic clinical trials Aliki AJODO 2020
Core outcomes
· Standardised outcomes measured as a minimum
· COMET project in medicine and dentistry – Core Outcome Measures in Effectiveness Trials core outcome measures in effectiveness trials COMET
· Advantages
o Future outcomes relevant to stakeholders
§ Patient, clinician, best evidence
o Less heterogeneity – allows better meta analysis
o Only ¼ of orthodontic systematic reviews contain meta-analysis Koletsi
o
· Method – followed COMET recommendations
o Mixed methods = systematic review and qualitative
o Combine outcomes from both = 34
o Consensus meeting with stakeholders
· Results
o 4 themes with 7 outcomes
§ Breakage appliance and teeth
§ Clinical outcomes, alignment, skeletal, stability
§ Delivery of care – patient related adherence
§ Perceived health status
· Conclusion
o Advise at least 1 outcome for each theme
